On the basis of analyzing the ecological problems of the Northwest Pacific region, we suggest ecological quality objectives, the attainment of which is to ensure a good state of the marine environment in the region which is a necessary condition for sustainable nature management. We discuss the operational goals and quantitative criteria and indicators as required for monitoring the current state of ecosystems as well as the progress in achieving the objectives. An analysis is made of experience in using a similar approach in the European Union. It is shown that there is a difference of the environmental quality monitoring techniques in the Northwest Pacific region where cooperative efforts on rationalization of nature management are not supported legislatively. In dealing with this problem, a special role would be played by regional and international cooperation, specifically within the United National Environment Programme in the Northwest Pacific region, contributing to a harmonization of the national monitoring systems. The need for international cooperation is also dictated by the irregularity of natural and socioeconomic conditions in the region, which makes the development of unified assessment methods difficult.Keywords: ecological quality objectives, ecological problems, UNEP NOWPAP Programme, marine environment quality indicators.