This paper considers land use dynamics within Aksai-Chatyrkul depression of the Inner Tian Shan for the period of last several decades. The territory of this alpine valley is used as pastures for livestock of Atbashy district — a traditional branch of agriculture in Naryn region. In this paper, for the first time the dynamics of alpine pasture land use in Aksai-Chatyrkul depression in recent years are analyzed, taking into account the climatic and anthropogenic changes. A map of land use at as scale of 1: 500 000, based on satellite imagery for the period of 1978–1980 as well as a map of monitoring observations of pastures in Naryn region for 2010 were used. The analysis and assessment of the spatial distribution and area changes of pastures from 1980 to 2010 were conducted. Due to the closing of representative Aksai and Chatyrkul weather stations in the study area the data from the closest weather stations of the Inner Tian-Shan with longest time series (Naryn and Tian Shan) were also used to reconstruct the time series of mean annual air temperature and annual precipitation. Trends of recent climate changes in Aksai-Chatyrkul area in 1930–2014 were identified according to the data of six weather stations. Selyaninovs hydrothermal coefficient for Aksai-Chatyrkul depression was calculated and the assessment of climatic and anthropogenic changes potential impact on land-use dynamics was made. Cartographic analysis of land use dynamics shows that there is a tendency of total pasture area reduction in Aksai-Chatyrkul depression, which reduced by up to 12.2 % from 1980 to 2010. For verification of the map documents the 2014–2015 field observation data were used. There is an increase in mean annual air temperature and a slight increase annual precipitation in the region during the period from 1930 to 2014, as well as a weak trend of aridization in Aksai-Chatyrkul area. These factors have very slight impact on land use dynamics in the region compared with anthropogenic factors.Keywords: monitoring, land use, climate changes, dynamics, the Inner Tian Shan.